郭和光, 邵国健, 吴丹青. 顶空气相色谱法测定工作场所空气中苦味酸[J]. 环境与职业医学, 2015, 32(1): 78-81. DOI: 10.13213/j.cnki.jeom.2015.14245
引用本文: 郭和光, 邵国健, 吴丹青. 顶空气相色谱法测定工作场所空气中苦味酸[J]. 环境与职业医学, 2015, 32(1): 78-81. DOI: 10.13213/j.cnki.jeom.2015.14245
GUO He-guang , SHAO Guo-jian , WU Dan-qing . Determination of Picric Acid in Workplace Air by Headspace Gas Chromatography[J]. Journal of Environmental and Occupational Medicine, 2015, 32(1): 78-81. DOI: 10.13213/j.cnki.jeom.2015.14245
Citation: GUO He-guang , SHAO Guo-jian , WU Dan-qing . Determination of Picric Acid in Workplace Air by Headspace Gas Chromatography[J]. Journal of Environmental and Occupational Medicine, 2015, 32(1): 78-81. DOI: 10.13213/j.cnki.jeom.2015.14245

顶空气相色谱法测定工作场所空气中苦味酸

Determination of Picric Acid in Workplace Air by Headspace Gas Chromatography

  • 摘要: 目的 建立顶空气相色谱测定工作场所空气中苦味酸的方法。

    方法 用微孔滤膜采集空气中苦味酸,纯水洗脱,次氯酸钠衍生顶空气相色谱电子捕获检测器检测。

    结果 苦味酸浓度在0.01~1.00 μg/mL范围内线性关系良好(r=0.999 7),本法检出限为0.000 06 μg/mL (进样量为100 μL),最低检出浓度为0.000 008 mg/m3(采样体积为75 L,解吸液体积为10 mL),相对标准偏差为1.42%~1.61%,平均回收率为97.9%~99.7%,平均洗脱效率为95.9%~97.3%,采样效率为95.1%~97.1%,微孔滤膜吸收10 μg苦味酸,在室温条件下保存,至少可稳定15 d。

    结论 该方法各项指标均符合GBZ/T 210.4-2008《职业卫生标准制定指南第4部分:工作场所空气中化学物质测定方法》的要求,适用于工作场所空气中苦味酸的检测。

     

    Abstract: Objective To establish a method to determine picric acid in workplace air by headspace gas chromatography.

    Methods Air samples containing picric acid were collected by millipore filter, eluted by pure water, and derivatized with sodium hypochlorite before determined by headspace gas chromatography-electron capture detector (GC-EDC).

    Results A good linearity (r=0.999 7) was obtained when the concentrations of picric acid were in the range from 0.01 μg/mL to 1.00 μg/mL. The detection limit was 0.000 06 μg/mL (100 μL injection volume), the minimum detectable concentration was 0.000 008 mg/m3 (calculation with 75 L sampling volume, 10 mL desorption volume), the relative standard deviation was 1.42%-1.61%, the average recovery rate was 97.9%-99.7%, the average elution efficiency was 95.9%-97.3%, and the sampling efficiency was 95.1%-97.1%. The millipore filters absorbed 10 μg picric acid, and were stable under room temperature for at least 15 days.

    Conclusion This determination method meets the requirements of Guide for Establishing Occupational Health Standards Part 4:Determination Methods of Air Chemicals in Workplace (GBZ/T 210.4-2008) and is suitable for the determination of picric acid in workplace air.

     

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