张海蕾, 王金富, 李颖芳, 方家阳, 张美辨. 1例乙型肝炎患者接触二甲基甲酰胺中毒报告[J]. 环境与职业医学, 2018, 35(7): 661-664. DOI: 10.13213/j.cnki.jeom.2018.18139
引用本文: 张海蕾, 王金富, 李颖芳, 方家阳, 张美辨. 1例乙型肝炎患者接触二甲基甲酰胺中毒报告[J]. 环境与职业医学, 2018, 35(7): 661-664. DOI: 10.13213/j.cnki.jeom.2018.18139
ZHANG Hai-lei, WANG Jin-fu, LI Ying-fang, FANG Jia-yang, ZHANG Mei-bian. A case report of hepatitis B combined with dimethylformamide poisoning[J]. Journal of Environmental and Occupational Medicine, 2018, 35(7): 661-664. DOI: 10.13213/j.cnki.jeom.2018.18139
Citation: ZHANG Hai-lei, WANG Jin-fu, LI Ying-fang, FANG Jia-yang, ZHANG Mei-bian. A case report of hepatitis B combined with dimethylformamide poisoning[J]. Journal of Environmental and Occupational Medicine, 2018, 35(7): 661-664. DOI: 10.13213/j.cnki.jeom.2018.18139

1例乙型肝炎患者接触二甲基甲酰胺中毒报告

A case report of hepatitis B combined with dimethylformamide poisoning

  • 摘要: 某乙肝患者在未进行岗前职业健康检查的情况下从事接触二甲基甲酰胺(DMF)作业,作业岗位空气中DMF浓度符合国家接触限值要求,但仍发生中毒事件,且病情严重,不排除乙型肝炎与DMF中毒两种病因交叉作用或协同作用的可能性。该病例诊断过程提示用人单位须重视职业卫生管理,履行职业病防治主体责任,做好上岗前职业健康检查,及时发现职业禁忌症,减少DMF接触机会,防止类似中毒事件的发生;职业卫生监管部门应加强对用人单位的监督管理,督促其履行职业病防治主体责任。

     

    Abstract: A case of severe occupational dimethylformamide (DMF) poisoning was reported. The worker was diagnosed as hepatitis B without pre-employment occupational health examination and exposed to DMF meeting the requirements of national exposure limits. No evidence supported to eliminate the potential interaction or synergistic effect between hepatitis B and DMF poisoning. The diagnosis process suggested that DMF exposure and similar poisoning incidents might be prevented through employers' attaching importance to occupational health management, fulfilling the principle responsibility for occupational disease prevention and treatment, performing pre-employment occupational health examinations, and timely detecting occupational contraindications; occupational health supervision departments should strengthen the supervision and management to employers, urging them to fulfill the principle responsibility for prevention and treatment of occupational diseases.

     

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