王航平, 孙振武. 低氧训练对肥胖人群身体成分和血脂影响的meta分析[J]. 环境与职业医学, 2019, 36(2): 157-163, 169. DOI: 10.13213/j.cnki.jeom.2019.18435
引用本文: 王航平, 孙振武. 低氧训练对肥胖人群身体成分和血脂影响的meta分析[J]. 环境与职业医学, 2019, 36(2): 157-163, 169. DOI: 10.13213/j.cnki.jeom.2019.18435
WANG Hang-ping, SUN Zhen-wu. Effects of hypoxic training on body composition and blood lipid in obese people: A meta analysis[J]. Journal of Environmental and Occupational Medicine, 2019, 36(2): 157-163, 169. DOI: 10.13213/j.cnki.jeom.2019.18435
Citation: WANG Hang-ping, SUN Zhen-wu. Effects of hypoxic training on body composition and blood lipid in obese people: A meta analysis[J]. Journal of Environmental and Occupational Medicine, 2019, 36(2): 157-163, 169. DOI: 10.13213/j.cnki.jeom.2019.18435

低氧训练对肥胖人群身体成分和血脂影响的meta分析

Effects of hypoxic training on body composition and blood lipid in obese people: A meta analysis

  • 摘要: 目的 运用meta分析法评估低氧训练对肥胖人群身体成分和血脂水平的影响。

    方法 检索PubMed、EBSCO、Medline, Central、中国期刊全文数据库、万方等中外期刊数据库, 收集有关低氧训练对肥胖人群身体成分及血脂影响的临床随机对照实验(RCT)文献。英文检索词为hypoxia training、hypoxia exercise、normobaric hypoxia training、clinical trial、randomized controlled trial、obesity、body mass index, 中文检索词为低氧训练、低氧运动、缺氧训练、临床试验、临床随机对照试验、肥胖、身体成分, 检索时限为从建库至2017年12月, 未进行语言限制。通过文献筛选后, 采用RevMan 5.3软件进行meta分析, 效应值以均数(MD)及其95%可信区间(95%CI)表示。

    结果 共纳入8个RCT, 205个单纯肥胖患者。低氧训练组与常氧训练组在体重指数(MD=-1.4, 95%CI:-2.54~-0.25, P < 0.001)、体脂率(MD=-0.84, 95%CI:-1.42~-0.26, P=0.004)和血液中总胆固醇水平(MD=-1.52, 95%CI:-2.98~-0.05, P=0.040)3个指标比较, 差异具有统计学意义; 而腰臀比、高密度脂蛋白、低密度脂蛋白、甘油三脂等指标的差异不具有统计学意义。不同干预时间和不同低氧训练模式是体重指数异质性的主要来源。低氧训练时间>4周的体重指数差异具有统计学意义(MD=-5.73, 95%CI:-9.36~-2.10, P < 0.001);间歇性低氧训练(MD=-0.94, 95%CI:-1.31~-0.74, P=0.050)的模式对肥胖者体重指数差异亦具有统计学意义。不同干预时间是血清总胆固醇水平异质性的主要来源, 低氧训练时间>4周的肥胖者总胆固醇水平差异具有统计学意义(MD=-2.42, 95%CI:-4.20~-0.65, P < 0.001)。

    结论 低氧训练>4周对肥胖者的体重指数和血清总胆固醇有影响。间歇性低氧训练对肥胖者的体重指数有改善作用。

     

    Abstract: Objective To clarify the effects of hypoxic training on body composition and lipid level of obese people by meta analysis method.

    Methods In this study, we searched PubMed, EBSCO, Medline, Central, Chinese Academic Journals Full-text Database, Wanfang databases from inception to December 2017 to collect literatures on the effects of hypoxia training on body composition and blood lipid of obese people by using search words in either English or Chinese such as hypoxia training, hypoxia exercise, normobaric hypoxia training, clinical trial, randomized controlled trial, obesity, and body mass index, without language restriction. After literature screening, meta analysis was conducted using RevMan 5.3 software, and effect values were reported as mean difference and 95% confidence interval.

    Results A total of 8 RCT and 205 obese patients were included. Body mass index (MD=-1.4, 95% CI:-2.54--0.25, P < 0.001), body fat percentage (MD=-0.84, 95% CI:-1.42-0.26, P=0.004), and total cholesterol concentration (MD=-1.52, 95% CI:-2.98--0.05, P=0.040) were statistically different between hypoxia training group and normoxia training group. However, waist-tohip ratio, high-density lipoprotein, low-density lipoprotein, and triglyceride were not. Different intervention time and different hypoxia training patterns were the main sources of heterogeneity in body mass index. Hypoxia training > 4 weeks affected body mass index (MD=-5.73, 95% CI:-9.36--2.10, P < 0.001); intermittent hypoxic training (MD=-0.94, 95% CI:-1.31--0.74, P=0.050) also affected body mass index of the obese people. Different intervention time was the main source of heterogeneity in total cholesterol concentration. Hypoxia training > 4 weeks affected total cholesterol concentration (MD=-2.42, 95% CI:-4.20--0.65, P < 0.001).

    Conclusion Hypoxia training > 4 weeks affects body mass index and serum total cholesterol of obese patients. Intermittent hypoxic training is effective for improving body mass index.

     

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