湘江河鲫鱼体内壬基酚、辛基酚和双酚A含量调查及健康风险评价
Survey of nonylphenol, octylphenol, and bisphenol A levels in crucian carp in Xiangjiang River and associated health risk assessment
-
摘要:
背景 湘江河是遵义地区水源水供应的主要河流。随着城镇工业化脚步加快，湘江河污染日益严重。在众多污染物中，典型环境内分泌干扰物壬基酚（NP）、辛基酚（OP）和双酚A（BPA）的污染值得重视。
目的 调查湘江河鲫鱼体内NP、OP和BPA的蓄积量及底泥中NP、OP和BPA的平均含量，并对其健康风险进行评估。
方法 2017年7月，在湘江河北郊水库至丁字口河段设置7个采样点采集鲫鱼样品，每个采样点采集6份样品。同时在采样河段采集底泥样品（n=7）。用高效液相色谱仪检测各采样点鲫鱼样品肌肉组织中NP、OP和BPA的含量和采样河段底泥样品中NP、OP和BPA的含量，并计算这三种物质的生物底泥富集因子（BSAF）和目标危害商数（THQ）。
结果 各采样点鲫鱼肌肉组织中均能检测出NP、OP和BPA，质量分数分别为（117.59±80.76）、（117.12±69.30）、（127.03±93.44）μg/kg（以湿重计）。第一人民医院采样点鲫鱼肌肉组织中NP、OP和BPA的含量最高，分别为最低浓度（北郊水库采样点）的3.61、2.37、11.15倍。底泥中NP、OP和BPA的质量分数分别为（589.8±352.4）、（528.5±404.5）、（377.5±228.0）μg/kg（以干重计）。鲫鱼肌肉组织中NP和OP（r=0.441，P=0.003）、NP和BPA（r=0.425，P=0.005）、OP和BPA（r=0.505，P=0.001）的质量分数均呈正相关关系。各采样点鲫鱼组织中NP、OP和BPA的BSAF小于4且THQ值小于1。
结论 本次调查的鲫鱼肌肉组织和底泥均存在NP、OP和BPA污染，暂未对人体产生健康风险。
Abstract:Background Xiangjiang River is the main source of water supply in Zunyi area. With the acceleration of urban industrialization, the pollution of Xiangjiang River is increasingly serious. Among many pollutants, nonylphenol (NP), octylphenol (OP), and bisphenol A (BPA), typical representatives of environmental endocrine disruptors, deserve attention.
Objective This study investigates the accumulation of NP, OP, and BPA in crucian carp in Xiangjiang River and the average contents of NP, OP, and BPA in sediment, and assesses associated human health risk.
Methods In July 2017, six crucian carp samples were collected at each of seven sampling sites from Beijiao Reservoir to Dingzikou Reach of Xiangjiang River. At the same time, seven sediment samples were collected in the sampling sites. The contents of NP, OP, and BPA in muscle tissues of crucian carp samples and in sediment samples were detected by high performance liquid chromatography. The biological sediment enrichment factor (BSAF) and target hazard quotient (THQ) of the three substances were calculated.
Results NP(117.59±80.76) μg/kg (in wet weight), OP(117.12±69.30) μg/kg (in wet weight), and BPA(127.03±93.44) μg/kg (in wet weight) were detected in muscle tissues of crucian carp samples at all sampling sites. The contents of NP, OP, and BPA in muscle tissues of crucian carp samples from the First People's Hospital sampling site were the highest, which were 3.61, 2.37, and 11.15 times of the identified lowest concentrations (Beijiao Reservoir sampling site). The contents of NP, OP, and BPA in sediment samples were (589.8±352.4), (528.5±404.5), and (377.5±228.0) μg/kg (in dry weight), respectively. There were significant positive correlations between the contents of NP and OP (r=0.441, P=0.003), NP and BPA (r=0.425, P=0.005), OP and BPA (r=0.505, P=0.001) in muscle tissues among the crucian carp samples. The BSAF and THQ values of NP, OP, and BPA in muscle tissues of crucian carp samples at each sampling site were less than 4 and 1, respectively.
Conclusion NP, OP, and BPA are positive in muscle tissues of crucian carp and sediment samples in the study river, and there is no health risk to human body.
下载:
