两种金黄色葡萄球菌产肠毒素差异的Meta分析
Comparative Prevalence of the Enterotoxin-producing Isolates in Two Strains of Saphylococcus Aureus Using Meta-analysis
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摘要:
目的 分析耐甲氧西林金黄色葡萄球菌(methicillin-resistant Staphylococcus aureus, MRSA)和甲氧西林敏感金黄色葡萄球菌(methicillin sensitive Staphylococcus aureus, MSSA)之间产生肠毒素的差异,为评价MRSA、MSSA与金黄色葡萄球菌食物中毒之间的关系提供参考依据。 方法 采用Meta分析方法对国内外1990~2008年发表的有关MRSA和MSSA产毒株率比较的文献进行汇总、归纳和统计分析。 结果 共检索到7篇文献,合并总RR值为2.18, 95%可信区间为1.58~2.99。MRSA中的产毒株率是MSSA的2.18倍。 结论 MRSA产生肠毒素的概率远大于MSSA。 Abstract:Objective To analysis the difference in enterotoxin production between methicillin-resistant Staphylococcus aureus (MRSA)and methicillin sensitive Staphylococcus aureus (MSSA)so as to provide a reference to evaluate their association with staphylococcus aureus food poisoning. Methods Meta-analysis was used to evaluate the data extracted from published articles domestic and abroad relevant to comparative prevalence of the enterotoxin-producing isolates in MRSA and MSSA during 1992-2008. Results A total of 7 articles were retrieved. The overall effect indicator RR (95%CI)was 2.18 (1.58-2.99). The prevalence of the enterotoxin-producing isolates in MRSA was 2.18 fold greater than in MSSA. Conclusion The probability of enterotoxin production in MRSA was far more than in MSSA.