噪声对作业工人高频听力损失及血清转氨酶的影响
Effects of Industrial Noise on High Frequency Hearing Loss and Transaminase in Workers
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摘要:
目的 探讨油田作业工人噪声对高频听力损失患病率和血清谷草转氨酶、谷丙转氨酶以及谷氨酰转肽酶的影响。 方法 采用横断面流行病学研究方法,对716名噪声作业工人和133名非噪声作业人员进行健康检查和听力测试,比较两组高频听力损失率,并检测其血清转氨酶进行比较。 结果 噪声组高频听力损失率30.73%(标化30.98%),明显高于非噪声组的23.31%(标化22.61%),差异有统计学意义(χ2=6.347, P=0.012)。噪声组中随年龄的增长高频听力损失率有增高的趋势(趋势χ2=4.917, P=0.027)。接触噪声工龄越长,高频听力损失率越高(趋势χ2=66.241,P=0.000)。噪声组谷草转氨酶、谷丙转氨酶与谷氨酰转肽酶均明显高于非噪声组(分别为t=3.185, P=0.002;t=2.907,P=0.004;t=2.801, P=0.006)。 结论 长期噪声作业可引起听力损失,且噪声能引起体内谷草转氨酶、谷丙转氨酶与谷氨酰转肽酶活性改变。 Abstract:Objective To explore the effect of occupational noise exposure on the prevalence of high frequency hearing loss (HFHL) as well as the activities of serum glutamic-oxaloacetic transaminase (SGOT),glutamate-pyruvate transaminase (GPT) and glutamyl transpeptidase (GTP) in workers. Methods A cross-sectional epidemiological study,including health examination and hearing test,was conducted among 716 workers exposed to industrial noise and 133 controls without noise exposure.Their prevalence of HFHL and serum transaminase were compared and analyzed. Results The prevalence of HFHL in the noise exposure group (30.73%) was significantly higher than that of the controls (23.31%)(χ2=6.347,P=0.012).The prevalence of HFHL in the noise exposure group was increased with age (linear-by-linear association χ2=4.917,P=0.027) and noise exposure years (linear-by-linear association χ2=66.241,P=0.000).Compared with the control group,the serum SGOT (t=3.185,P=0.002),GPT (t=2.907,P=0.004),and GTP (t=2.801,P=0.006) were all increased greatly in the noise exposure group. Conclusion Hearing loss can be caused by long-term noise exposure.In addition,noise can induce changes in activities of serum transaminase.
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