上海市浸润性子宫颈癌死亡现况及趋势分析
Current Mortality and Its Temporal Trend of Invasive Cervical Cancer in Shanghai
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摘要:
目的 分析上海市浸润性子宫颈癌的死亡特征及其趋势。 方法 利用上海市死因监测系统收集的子宫颈癌死亡病例资料,运用年度变化百分比对上海市1974-2011年浸润性子宫颈癌死亡率的时间趋势进行分析。 结果 上海是浸润性子宫颈癌死亡率相对较低的地区,2007-2011年的粗死亡率为2.48/10万,标化死亡率为1.26/10万,市区死亡率均高于郊区,与1974-1978年相比,死亡中位年龄提前7岁,30~44岁的死亡率高于1974-1978年同年龄组值。1974至2011年,浸润性子宫颈癌标化死亡率共下降84.04%。阶段趋势分析显示,自1999年始,上海市区浸润性子宫颈癌的标化死亡率由下降转为上升,郊区女性的死亡率由降转为升的时间点为1997年,自1993年起,35~44岁年龄段人群死亡率就开始由下降转为上升。 结论 上海市浸润性子宫颈癌死亡率处于较低水平;子宫颈癌死亡年轻化趋势明显。从1999年开始,浸润性子宫颈癌标化死亡率由下降转为上升,主要由于55岁以上女性死亡率上升所致。未来应加强对子宫颈癌的筛查普及,尤其是年轻女性,同时应加强规范化诊治,降低子宫颈癌的死亡率。 Abstract:Objective To describe characteristics of invasive cervical cancer (ICC) mortality and analyze its temporal trend. Methods Based on the mortality data of ICC in Shanghai Death Registration System, annual percentage change (APC) was used to analyze the temporal trend of mortality from ICC from 1974 to 2011. Results The ICC mortality was relatively low in Shanghai. In 2007-2011, the crude mortality of ICC was 2.48/100 000 and the standardized mortality was 1.26/100 000. The mortality of ICC in Shanghai urban areas was higher than that in the suburbs. Compared with the period of 1974-1978, the median age of ICC deaths between 2007 and 2011 decreased 7 years, and the mortality rate in the age group of 30-44 years was higher than its counterpart in 1974-1978. The standardized ICC mortality decreased 84.04% from 1974 to 2011. However, the results of temporal trend analysis demonstrated an increasing ICC standardized mortality from 1999. The ICC fatalities in the suburbs showed a decreasing trend before 1997 and a rising trend after 1997. A downward trend of ICC mortality before 1993 and then an upward one after 1993 were identified in the ICC fatalities of the age group of 35-44 years. Conclusion Although the ICC mortality is low in Shanghai, there is an obviously increasing mortality in the younger age group. From 1999, the ICC mortality in Shanghai began to rise, which was mostly contributed by the age group of 55 years or older. Mass screening is needed in future examinations, especially for young women. The standardization of diagnosis and treatment should also be strengthened to reduce cervical cancer mortality.
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