Abstract: Meteorological factors have been recognized as one group of triggers to childhood asthma attack. Developing warning services of meteorological public health are the important approaches to improve the quality of public health services. The aim of the study is to establish a weather-based early warning model of childhood asthma by using Shanghai medical and meteorological information resources. The correlation coefficient between forcast and actual values was 0.634. Early warning products of childhood asthma were developed upon the model warning results and a weather-based early warning service system for childhood asthma was established using information technique. The system will provide relevant service to residents, school health care teachers, parents and susceptible population.