ZHOU Mei-ling, YAO Ming-dong, LI Minjie. Simultaneous determination of chlorfenapyr, fipronil, and bifenthrin in cabbage powder by gas chromatography-triple quadrupole mass spectrometry[J]. Journal of Environmental and Occupational Medicine, 2020, 37(12): 1206-1210. DOI: 10.13213/j.cnki.jeom.2020.20247
Citation: ZHOU Mei-ling, YAO Ming-dong, LI Minjie. Simultaneous determination of chlorfenapyr, fipronil, and bifenthrin in cabbage powder by gas chromatography-triple quadrupole mass spectrometry[J]. Journal of Environmental and Occupational Medicine, 2020, 37(12): 1206-1210. DOI: 10.13213/j.cnki.jeom.2020.20247

Simultaneous determination of chlorfenapyr, fipronil, and bifenthrin in cabbage powder by gas chromatography-triple quadrupole mass spectrometry

  • Background Chlorfenapyr, fipronil, and bifenthrin residues tend to remain in food and have potential hazards to human and animal health. At present, there are few methods to detect the three pesticides at the same time. Therefore, it is necessary to establish a sensitive and accurate detection method.
    Objective This methodological study aims to establish gas chromatography-triple quadrupole mass spectrometry to determine chlorfenapyr, fipronil, and bifenthrin in cabbage powder by optimizing gas chromatography and mass spectrometry conditions.
    Methods After optimizing solvent extraction and purification during pretreatment, gas chromatography-triple quadrupole mass spectrometry in multiple reaction monitoring mode was used to select target ion pairs for determination. The external standard method was also used for quantitative determination.
    Results Under the proposed optimal conditions using acetonitrile as the extraction solvent, magnesium sulfate and sodium chloride as the extraction salts, and PSA glass column solid phase extraction, there were good linear relationships of chlorfenapyr, fipronil, and bifenthrin in the range of 0.01-0.2 mg·L-1 (r>0.998); the sample recovery rates were 84.4%-109.0%, 93.4%-106.8%, and 101.8%-108.2%, respectively; the relative standard deviations were 7.3%-8.9%, 5.2%-6.9%, and 4.5%-7.5%, respectively.
    Conclusion The gas chromatography-triple quadrupole mass spectrometry method can achieve the simultaneous and accurate determination of chlorfenapyr, fipronil, and bifenthrin in cabbage powder.
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