Application of percutaneous lung biopsy to diagnosis and differential diagnosis of pneumoconiosis: Four case reports
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Abstract
Percutaneous lung biopsy was ordered for four silicosis-suspected cases to obtain lung tissues for pathological examination and to confirm the presence of pathogenic dust and corresponding characteristic changes in lung tissues or the pathological evidence of other pulmonary diseases such as tuberculosis and tumor. Finally, 1 case with definite occupational history, who did not show any specific alterations in pulmonary image but features of giant cell interstitial pneumonia by pathological examination, was diagnosed as hard metal lung disease; 1 case whose occupational history was incompatible with image changes and who showed typical hyaline changes by pathological examination was diagnosed as the third phase of silicosis; 1 case without definite occupational history, who showed features of tuberculosis by pathological examination, was diagnosed as tuberculosis; and 1 case with lung mass shadow and silicosis, who showed tumor-like changes by pathological examination, was diagnosed as silicosis combined with lung cancer. Therefore, obtaining pathological specimens through CT-guided percutaneous lung biopsy has positive significance in the diagnosis and differential diagnosis of pneumoconiosis.
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