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QIU Yue-feng , LIN Yong , HUANG Meng , CHEN Xing , HE Fei , FAN Li-hui , CHEN Jun-lei , CAI Lin . Association of Smoking, Residential Environment and Polymorphisms with Lung Cancer[J]. Journal of Environmental and Occupational Medicine, 2011, 28(3): 133-136,140.
Citation: QIU Yue-feng , LIN Yong , HUANG Meng , CHEN Xing , HE Fei , FAN Li-hui , CHEN Jun-lei , CAI Lin . Association of Smoking, Residential Environment and Polymorphisms with Lung Cancer[J]. Journal of Environmental and Occupational Medicine, 2011, 28(3): 133-136,140.
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Association of Smoking, Residential Environment and Polymorphisms with Lung Cancer

    Abstract
  • Objective To reveal risk factors of lung cancer.

    Methods A case-control study was designed with 781 lung cancer patients and 781 control subjects. Both epidemiological investigation and laboratory examination were performed in every subject.

    Results We revealed that smoke during cooking, irritant smell after decoration, insufficient ventilation, smoking and cooking presented increased risk of developing lung cancer. The low temperature of oil during cooking and rs144848 C allele were identified as protective factors. Smoking, smoke during cooking and living in bungalow showed a synergic effect.

    Conclusion The results suggest that smoking and air pollution are associated with lung caner. Rs144848 C allele may have protective effect on lung cancer.

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