Author Submission Open Access
Advance Search
GAO Hong-xia , LIU Ying-li , YAN Hong , CHANG Yu-rong . Hepatic and Renal Oxidative Damage of Organic Pollutants in the Soil of Sewage Irrigation Area on Mice[J]. Journal of Environmental and Occupational Medicine, 2010, 27(1): 34-35.
Citation: GAO Hong-xia , LIU Ying-li , YAN Hong , CHANG Yu-rong . Hepatic and Renal Oxidative Damage of Organic Pollutants in the Soil of Sewage Irrigation Area on Mice[J]. Journal of Environmental and Occupational Medicine, 2010, 27(1): 34-35.
shu

Hepatic and Renal Oxidative Damage of Organic Pollutants in the Soil of Sewage Irrigation Area on Mice

    Abstract
  • Objective To study the oxidative damage of organic extraction of the soil in sewage irrigation area on liver and kidney of mice.

    Methods Organic extractions were obtained from the soil in pollution area and control area by supersonic, and to feed the mice by garage in different doses(once each day for 14 days). Reagent(Dimethyl sulfoxide)was fed in control group. MDA, T-SOD, and GSH-Px in liver and kidney were detected.

    Results Compared with the reagent control group, MDA(1.18 nmol/mg.prot), GSH-Px (239.97 U/mg.prot) in liver were decreased in the high-dose group of the sewage irrigation area, T-SOD (119.70 and 76.72 U/mg.prot)in liver was decreased in the low-dose group and in the high-dose group of the sewage irrigation area (P<0.05 or P<0.01), GSH-Px(133.12 U/mg.prot)in kidney was decreased in both groups of the sewage irrigation area(P<0.05).

    Conclusion Organic extraction of the soil in sewage irrigation area could induce hepatic and renal oxidative damage in mice.

    • FullText(HTML)
  • loading
    • References (0)
    • Relative Articles
  • Supplements (0)

Catalog

  • wechat

    • WeChat

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return