十溴二苯乙烷的环境分布及其毒性效应研究进展

Research progress on environmental distribution and toxicity effects of decabromodiphenyl ethane

  • 摘要: 十溴二苯乙烷(DBDPE)是一种新型溴系阻燃剂,是十溴联苯醚的主要替代品,广泛应用于电子电器、塑料制品及纺织品等工业制品中,其在生产、使用及产品废弃过程中均容易通过挥发或渗溢等方式进入周围环境,并产生生物富集、生物放大现象。中国作为电子产品制造大国,对DBDPE的需求及其产量迅速增长,DBDPE的广泛应用所带来的环境污染与毒性效应也备受关注。目前,涉及DBDPE环境分布的研究数据较多,其广泛存在于大气、土壤、沉积物、污泥、室内外粉尘中;然而DBDPE毒性效应相关的研究较少,毒作用机理尚不清楚。本文综述了DBDPE的环境分布和毒性效应研究进展,首先总结了DBDPE在环境和生物体的分布;然后介绍了DBDPE的毒性效应,如生殖发育毒性、甲状腺激素干扰毒性、肝肾毒性、神经毒性、心血管毒性等,特别是对生殖发育毒性和甲状腺激素干扰毒性进行详细阐述;最后分析了其可能的毒作用机制,为后续研究提供参考依据。

     

    Abstract: Decabromodiphenyl ethane (DBDPE) is a new brominated flame retardant and the main substitute of decabromodiphenyl ether, widely used in electronic appliances, plastic products, textiles, and other industrial products. It can enter the surrounding environment through volatilization or effusion in the process of production, use, and disposal, and result in biological enrichment and amplification. China as a large manufacturer of electronic products has rapidly increased its production capacity for DBDPE to meet the steeply climbing demand, and also pay attention to the environmental pollution and toxic effects brought by its extensive application. At present, much research has been conducted to describe the environmental distribution of DBDPE, as it widely exists in atmosphere, soil, sediment, sludge, and outdoor dust. However, there are few studies on the toxic effects of DBDPE, and the relevant mechanisms remain unclear. This review focused on the research progress on the environmental distribution and toxic effects of DBDPE. It started with the distribution of DBDPE in the environment and organisms; then summarized the toxic effects of DBDPE, such as reproductive and developmental toxicity, thyroid hormone disruption toxicity, liver and kidney toxicity, neurotoxicity, and cardiovascular toxicity, with detailed information about the first two; and finally compiled the possible mechanisms of its toxicity, aiming to provide new ideas and insights for further research.

     

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