Objective To measure the concentrations of organochlorine pesticides (OCPs) accumulated in the serum of non-occupationally exposed population in Shanxi Province.
Methods Blood samples were collected from 360 males and 240 females between 21-65 years old with no pesticide exposure history from Shanxi Province. Gas chromatography electron capture detector (GC-ECD) was used to quantify the accumulative concentrations of 21 OCPs in serum. Spearman's rank was performed to determine the correlations between accumulated OCPs concentrations and blood lipid or body mass index (BMI).
Results Higher levels M (P25~P75) in males of γ-HCH 42.38 (32.65~52.64) ng/g fat mass, aldrin 65.55 (51.26~83.29) ng/g fat mass, heptachlor 62.57 (38.73~157.87) ng/g fat mass, heptachlor epoxide 32.75 (ND~49.34) ng/g fat mass, endosulfan sulfate 53.96 (28.20~134.14) ng/g fat mass, and dieldrin 19.60 (ND~31.50) ng/g fat mass were found versus females (P < 0.05 or P < 0.01). There was a positive correlation between the serum concentrations of HCHs, O, P'-DDT, aldrin and blood lipid (P < 0.05 or P < 0.01), but no significant difference was found between serum OCPs and BMI.
Conclusion The OCPs have a certain accumulation in the investigated population, and the concentrations are associated with gender and blood lipid.
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