Objective To describe the temporal trend for incidence of thyroid cancer(TC) in Shanghai and to provide reference for further studies and control strategies.
Methods Annual TC incidence data within the period of 1981-2010 for urban Shanghai was provided by Shanghai Cancer Registry System. The calculation of age-standardized incidence rates(ASIRs) was based on world standard population. Average annual percentage of change(AAPC) and Joinpoint software from US National Cancer Institute were used to describe the trend for TC. Z test was used to distinguish the difference of ASIRs.
Results During 1981-2010, the temporal variation of ASIRs for TC for urban residents in Shanghai had ascending trends with a male AAPC of 7.71%(95% CI: 6.50%-8.95%) and a female AAPC of 7.05%(95% CI: 4.97%-9.18%). The ASIRs for female TC were 2.59-4.09 times as high as those for male TC in urban Shanghai. All ASIRs of TC for the urban residents had rising trends with AAPCs over 13% except those aged 0-19 years. The population with high risks of TC was gradually concentrated in the 45-64 years age group. During the period of 2002-2010, papillary cancer was the dominant type with proportions over 53% of total types of TC. The ASIRs of 2007-2010 from papillary, follicular, and female medullary cancers were at least double the respective levels of 2002-2006.
Conclusion The rising trend of TC in Shanghai is similar to those in the global and some developed countries. Improvement of the evaluation and research on factors associated with TC will help to clarify the epidemiological features about TC in Shanghai and promote more efficient control and prevention strategies.
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