CHE Chong-liang, FAN Hong-min, XIAO Meng-ying, WANG Chao-yang, GAO Xue-juan, LU Yao, CONG Long-xue, YUAN Ju-xiang, HU Po, LI Xiao-ming, MA Shi-tou. Dose-response relationship between shift work years and diabetes mellitus type 2 in male steel workers[J]. Journal of Environmental and Occupational Medicine, 2017, 34(6): 503-510. DOI: 10.13213/j.cnki.jeom.2017.16633
Citation: CHE Chong-liang, FAN Hong-min, XIAO Meng-ying, WANG Chao-yang, GAO Xue-juan, LU Yao, CONG Long-xue, YUAN Ju-xiang, HU Po, LI Xiao-ming, MA Shi-tou. Dose-response relationship between shift work years and diabetes mellitus type 2 in male steel workers[J]. Journal of Environmental and Occupational Medicine, 2017, 34(6): 503-510. DOI: 10.13213/j.cnki.jeom.2017.16633

Dose-response relationship between shift work years and diabetes mellitus type 2 in male steel workers

  • Objective To assess the dose-response relationship between male steel workers' shift work years and prevalence of diabetes mellitus type 2 (T2DM).

    Methods A total of 7 415 male steel workers were enrolled to occupational health examination and health examination from February 2015 to February 2016 in a hospital of steel company, and 7 209 questionnaires were included in the current crosssectional analysis. Data were collected on demographic characteristics, lifestyle, medical history, family history, height, weight, and occupational history of the participants. Multiple non-conditional logistic regression model and restricted cubic spline model were used to assess the relationship between shift work years and prevalence of T2DM in the selected male steel workers.

    Results The prevalence rate of T2DM was 16.5% in the participants. Previous shift work (OR=1.403, 95%CI: 1.131-1.740) and current shift work (OR=1.536, 95%CI: 1.298-1.817) were associated with T2DM (P < 0.05). After adjusting for general factors and occupational factors such as high temperature exposure, the above two factors were still associated with the prevalence rate of T2DM (P < 0.05), with ORs (95%CI) being 2.792 (2.286-3.411) and 2.546 (2.076-3.124), respectively. There was a significant correlation (χ2=35.00, P < 0.000 1) and a nonlinear correlation (χ2=3.00, P=0.606 8) between previous shift work years and T2DM. There was also a significant correlation (χ2=49.92, P < 0.000 1) and a nonlinear correlation (χ2=5.33, P=0.148 9) between current shift work years and T2DM.

    Conclusion Shift work years are associated to the prevalence of T2DM in a nonlinear pattern in male steel workers.

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